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mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility

Formin is one of the two major classes of actin binding proteins (ABPs) with nucleation and polymerization activity. However, despite advances in our understanding of its biochemical activity, whether and how formins generate specific architecture of the actin cytoskeleton and function in a physiolo...

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Detalles Bibliográficos
Autores principales: Sakamoto, Satoko, Thumkeo, Dean, Ohta, Hiroshi, Zhang, Zhen, Huang, Shuangru, Kanchanawong, Pakorn, Fuu, Takayoshi, Watanabe, Sadanori, Shimada, Kentaro, Fujihara, Yoshitaka, Yoshida, Shosei, Ikawa, Masahito, Watanabe, Naoki, Saitou, Mitinori, Narumiya, Shuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175529/
https://www.ncbi.nlm.nih.gov/pubmed/30256801
http://dx.doi.org/10.1371/journal.pbio.2004874