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MicroRNA-200a Targets Cannabinoid Receptor 1 and Serotonin Transporter to Increase Visceral Hyperalgesia in Diarrhea-predominant Irritable Bowel Syndrome Rats

BACKGROUND/AIMS: MicroRNAs (miRNAs) were reported to be responsible for intestinal permeability in diarrhea-predominant irritable bowel syndrome (IBS-D) rats in our previous study. However, whether and how miRNAs regulate visceral hypersensitivity in IBS-D remains largely unknown. METHODS: We establ...

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Detalles Bibliográficos
Autores principales: Hou, Qiuke, Huang, Yongquan, Zhang, Changrong, Zhu, Shuilian, Li, Peiwu, Chen, Xinlin, Hou, Zhengkun, Liu, Fengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Neurogastroenterology and Motility 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175558/
https://www.ncbi.nlm.nih.gov/pubmed/30347941
http://dx.doi.org/10.5056/jnm18037