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Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh

Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...

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Detalles Bibliográficos
Autores principales: Oh, SeCheol, Boudker, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175574/
https://www.ncbi.nlm.nih.gov/pubmed/30255846
http://dx.doi.org/10.7554/eLife.37291