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Free fatty acids reduce metabolic stress and favor a stable production of heterologous proteins in Pichia pastoris
The growth of yeasts in culture media can be affected by many factors. For example, methanol can be metabolized by other pathways to produce ethanol, which acts as an inhibitor of the heterologous protein production pathway; oxygen concentration can generate aerobic or anaerobic environments and aff...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175731/ https://www.ncbi.nlm.nih.gov/pubmed/29705163 http://dx.doi.org/10.1016/j.bjm.2018.03.008 |