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Apoptosis inducing factor deficiency causes retinal photoreceptor degeneration. The protective role of the redox compound methylene blue

Dysfunction in mitochondrial oxidative phosphorylation (OXPHOS) underlies a wide spectrum of human ailments known as mitochondrial diseases. Deficiencies in complex I of the electron transport chain (ETC) contribute to 30–40% of all cases of mitochondrial diseases, and leads to eye disease including...

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Detalles Bibliográficos
Autores principales: Mekala, Naveen K., Kurdys, Jacob, Depuydt, Mikayla M., Vazquez, Edwin J., Rosca, Mariana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175772/
https://www.ncbi.nlm.nih.gov/pubmed/30300862
http://dx.doi.org/10.1016/j.redox.2018.09.023