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Expression of the Immune Checkpoint Modulator OX40 in Acute Lymphoblastic Leukemia Is Associated with BCR-ABL Positivity()

OX40 and its ligand are members of the TNF/TNF receptor superfamily, which includes various molecules influencing cellular signaling and function of both tumor and immune cells. The ability of OX40 to promote proliferation and differentiation of activated T cells fueled present attempts to modulate...

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Detalles Bibliográficos
Autores principales: Rothfelder, Kathrin, Hagelstein, Ilona, Roerden, Malte, Blumenstock, Gunnar, Hofmann, Martin, Nuebling, Tina, Jung, Gundram, Salih, Helmut Rainer, Dörfel, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175778/
https://www.ncbi.nlm.nih.gov/pubmed/30300827
http://dx.doi.org/10.1016/j.neo.2018.09.005