Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence

Oesophageal cancer (OC) has high mortality. This study aims at determining the feasibility of liquid biopsies for genomic profiling in early stage OC, comparing two different technologies for mutational analysis in circulating cell -free DNA (ccfDNA) and evaluating the clinical impact of these somat...

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Detalles Bibliográficos
Autores principales: Pasternack, Helen, Fassunke, Jana, Plum, Patrick Sven, Chon, Seung-Hun, Hescheler, Daniel Alexander, Gassa, Asmae, Merkelbach-Bruse, Sabine, Bruns, Christiane Josephine, Perner, Sven, Hallek, Michael, Büttner, Reinhard, Bollschweiler, Elfriede, Hölscher, Arnulf Heinrich, Quaas, Alexander, Zander, Thomas, Weiss, Jonathan, Alakus, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175817/
https://www.ncbi.nlm.nih.gov/pubmed/30297788
http://dx.doi.org/10.1038/s41598-018-33027-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175817/
https://www.ncbi.nlm.nih.gov/pubmed/30297788
http://dx.doi.org/10.1038/s41598-018-33027-4

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