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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

Studies of cancer cell migration have found two modes: one that is protease-independent, requiring micron-sized pores or channels for cells to squeeze through, and one that is protease-dependent, relevant for confining nanoporous matrices such as basement membranes (BMs). However, many extracellular...

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Detalles Bibliográficos
Autores principales: Wisdom, Katrina M., Adebowale, Kolade, Chang, Julie, Lee, Joanna Y., Nam, Sungmin, Desai, Rajiv, Rossen, Ninna Struck, Rafat, Marjan, West, Robert B., Hodgson, Louis, Chaudhuri, Ovijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175826/
https://www.ncbi.nlm.nih.gov/pubmed/30297715
http://dx.doi.org/10.1038/s41467-018-06641-z