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Porphyromonas gingivalis bypasses epithelial barrier and modulates fibroblastic inflammatory response in an in vitro 3D spheroid model

Porphyromonas gingivalis-induced inflammatory effects are mostly investigated in monolayer cultured cells. The aim of this study was to develop a 3D spheroid model of gingiva to take into account epithelio-fibroblastic interactions. Human gingival epithelial cells (ECs) and human oral fibroblasts (F...

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Detalles Bibliográficos
Autores principales: Bugueno, Isaac Maximiliano, Batool, Fareeha, Keller, Laetitia, Kuchler-Bopp, Sabine, Benkirane-Jessel, Nadia, Huck, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175856/
https://www.ncbi.nlm.nih.gov/pubmed/30297793
http://dx.doi.org/10.1038/s41598-018-33267-4