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Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
Infection of specific pathogen-free mice with lymphocytic choriomeningitis virus (LCMV) is a widely used model to study antiviral T-cell immunity. Infections in the real world, however, are often accompanied by coinfections with unrelated pathogens. Here we show that in mice, systemic coinfection wi...
Autores principales: | Straub, Tobias, Freudenberg, Marina A., Schleicher, Ulrike, Bogdan, Christian, Gasteiger, Georg, Pircher, Hanspeter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175863/ https://www.ncbi.nlm.nih.gov/pubmed/30297690 http://dx.doi.org/10.1038/s41467-018-06609-z |
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