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Identification of a Novel OX40L(+) Dendritic Cell Subset That Selectively Expands Regulatory T cells

We have previously shown GM-CSF derived bone-marrow dendritic cells (G-BMDCs) can induce the selective expansion of Tregs through the surface-bound molecule OX40L; however, the physiological role of this ex vivo derived DC subset remained to be elucidated. We determined GM-CSF administration to mice...

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Detalles Bibliográficos
Autores principales: Marinelarena, Alejandra, Bhattacharya, Palash, Kumar, Prabhakaran, Maker, Ajay V., Prabhakar, Bellur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175872/
https://www.ncbi.nlm.nih.gov/pubmed/30297856
http://dx.doi.org/10.1038/s41598-018-33307-z