A Natural Deep Eutectic Solvent Formulated to Stabilize β-Lactam Antibiotics

β-lactam antibiotics, such as penicillin share a very unstable chemical structure. In water-based solutions, such as those used for clinical applications, the β-lactam ring is readily opened due to a nucleophilic or electrophilic attack, leading to the loss of antimicrobial activity. Since the achie...

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Detalles Bibliográficos
Autores principales: Olivares, Belén, Martínez, Fabián, Rivas, Lina, Calderón, Cristian, M. Munita, José, R. Campodonico, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175898/
https://www.ncbi.nlm.nih.gov/pubmed/30297853
http://dx.doi.org/10.1038/s41598-018-33148-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175898/
https://www.ncbi.nlm.nih.gov/pubmed/30297853
http://dx.doi.org/10.1038/s41598-018-33148-w

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