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A Natural Deep Eutectic Solvent Formulated to Stabilize β-Lactam Antibiotics
β-lactam antibiotics, such as penicillin share a very unstable chemical structure. In water-based solutions, such as those used for clinical applications, the β-lactam ring is readily opened due to a nucleophilic or electrophilic attack, leading to the loss of antimicrobial activity. Since the achie...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175898/ https://www.ncbi.nlm.nih.gov/pubmed/30297853 http://dx.doi.org/10.1038/s41598-018-33148-w |