Typing tumors using pathways selected by somatic evolution

Many recent efforts to analyze cancer genomes involve aggregation of mutations within reference maps of molecular pathways and protein networks. Here, we find these pathway studies are impeded by molecular interactions that are functionally irrelevant to cancer or the patient’s tumor type, as these...

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Detalles Bibliográficos
Autores principales: Wang, Sheng, Ma, Jianzhu, Zhang, Wei, Shen, John Paul, Huang, Justin, Peng, Jian, Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175900/
https://www.ncbi.nlm.nih.gov/pubmed/30297789
http://dx.doi.org/10.1038/s41467-018-06464-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175900/
https://www.ncbi.nlm.nih.gov/pubmed/30297789
http://dx.doi.org/10.1038/s41467-018-06464-y

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