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Enhanced validation of antibodies for research applications

There is a need for standardized validation methods for antibody specificity and selectivity. Recently, five alternative validation pillars were proposed to explore the specificity of research antibodies using methods with no need for prior knowledge about the protein target. Here, we show that thes...

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Detalles Bibliográficos
Autores principales: Edfors, Fredrik, Hober, Andreas, Linderbäck, Klas, Maddalo, Gianluca, Azimi, Alireza, Sivertsson, Åsa, Tegel, Hanna, Hober, Sophia, Szigyarto, Cristina Al-Khalili, Fagerberg, Linn, von Feilitzen, Kalle, Oksvold, Per, Lindskog, Cecilia, Forsström, Björn, Uhlen, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175901/
https://www.ncbi.nlm.nih.gov/pubmed/30297845
http://dx.doi.org/10.1038/s41467-018-06642-y