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Computational B-cell epitope identification and production of neutralizing murine antibodies against Atroxlysin-I

Epitope identification is essential for developing effective antibodies that can detect and neutralize bioactive proteins. Computational prediction is a valuable and time-saving alternative for experimental identification. Current computational methods for epitope prediction are underused and underv...

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Detalles Bibliográficos
Autores principales: Kozlova, Edgar Ernesto Gonzalez, Cerf, Loïc, Schneider, Francisco Santos, Viart, Benjamin Thomas, NGuyen, Christophe, Steiner, Bethina Trevisol, de Almeida Lima, Sabrina, Molina, Franck, Duarte, Clara Guerra, Felicori, Liza, Chávez-Olórtegui, Carlos, Machado-de-Ávila, Ricardo Andrez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175905/
https://www.ncbi.nlm.nih.gov/pubmed/30297733
http://dx.doi.org/10.1038/s41598-018-33298-x