High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

Optogenetic silencing allows time-resolved functional interrogation of defined neuronal populations. However, the limitations of inhibitory optogenetic tools impose stringent constraints on experimental paradigms. The high light power requirement of light-driven ion pumps and their effects on intrac...

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Detalles Bibliográficos
Autores principales: Mahn, Mathias, Gibor, Lihi, Patil, Pritish, Cohen-Kashi Malina, Katayun, Oring, Shir, Printz, Yoav, Levy, Rivka, Lampl, Ilan, Yizhar, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175909/
https://www.ncbi.nlm.nih.gov/pubmed/30297821
http://dx.doi.org/10.1038/s41467-018-06511-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175909/
https://www.ncbi.nlm.nih.gov/pubmed/30297821
http://dx.doi.org/10.1038/s41467-018-06511-8

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