Biosynthetic energy cost for amino acids decreases in cancer evolution

Rapidly proliferating cancer cells have much higher demand for proteinogenic amino acids than normal cells. The use of amino acids in human proteomes is largely affected by their bioavailability, which is constrained by the biosynthetic energy cost in living organisms. Conceptually distinct from gen...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Wang, Yirong, Li, Jun, Chen, Han, He, Xionglei, Zhang, Huiwen, Liang, Han, Lu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175916/
https://www.ncbi.nlm.nih.gov/pubmed/30297703
http://dx.doi.org/10.1038/s41467-018-06461-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175916/
https://www.ncbi.nlm.nih.gov/pubmed/30297703
http://dx.doi.org/10.1038/s41467-018-06461-1

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