The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells

The preservation of germ cell sexual identity is essential for gametogenesis. Here we show that H3K9me3-mediated gene silencing is integral to female fate maintenance in Drosophila germ cells. Germ cell specific loss of the H3K9me3 pathway members, the H3K9 methyltransferase SETDB1, WDE, and HP1a, l...

Descripción completa

Detalles Bibliográficos
Autores principales: Smolko, Anne E., Shapiro-Kulnane, Laura, Salz, Helen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175928/
https://www.ncbi.nlm.nih.gov/pubmed/30297796
http://dx.doi.org/10.1038/s41467-018-06697-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175928/
https://www.ncbi.nlm.nih.gov/pubmed/30297796
http://dx.doi.org/10.1038/s41467-018-06697-x

Ejemplares similares