A comprehensive overview of genomic imprinting in breast and its deregulation in cancer

Genomic imprinting plays an important role in growth and development. Loss of imprinting (LOI) has been found in cancer, yet systematic studies are impeded by data-analytical challenges. We developed a methodology to detect monoallelically expressed loci without requiring genotyping data, and applie...

Descripción completa

Detalles Bibliográficos
Autores principales: Goovaerts, Tine, Steyaert, Sandra, Vandenbussche, Chari A., Galle, Jeroen, Thas, Olivier, Van Criekinge, Wim, De Meyer, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175939/
https://www.ncbi.nlm.nih.gov/pubmed/30297886
http://dx.doi.org/10.1038/s41467-018-06566-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175939/
https://www.ncbi.nlm.nih.gov/pubmed/30297886
http://dx.doi.org/10.1038/s41467-018-06566-7

Ejemplares similares