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Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs...

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Detalles Bibliográficos
Autores principales: Lin, Zhenwu, Thorenoor, Nithyananda, Wu, Rongling, DiAngelo, Susan L., Ye, Meixia, Thomas, Neal J., Liao, Xiaojie, Lin, Tony R., Warren, Stuart, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175982/
https://www.ncbi.nlm.nih.gov/pubmed/30333828
http://dx.doi.org/10.3389/fimmu.2018.02256