Ligand Recognition Determines the Role of Inhibitory B Cell Co-receptors in the Regulation of B Cell Homeostasis and Autoimmunity

B cells express various inhibitory co-receptors including CD22, CD72, and Siglec-G. These receptors contain immunoreceptor tyrosine-based inhibition motifs (ITIMs) in the cytoplasmic region. Although many of the inhibitory co-receptors negatively regulate BCR signaling by activating SH2-containing p...

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Detalles Bibliográficos
Autor principal: Tsubata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175988/
https://www.ncbi.nlm.nih.gov/pubmed/30333834
http://dx.doi.org/10.3389/fimmu.2018.02276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175988/
https://www.ncbi.nlm.nih.gov/pubmed/30333834
http://dx.doi.org/10.3389/fimmu.2018.02276

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