TACI Isoforms Regulate Ligand Binding and Receptor Function

TACI signals activate B cell proliferation, isotype switch and antibody production in both normal immunity and autoimmune states. In contrast to murine TACI, the human TACI gene undergoes alternative splicing to produce short and long isoforms (TACI-S and TACI-L). In previous studies, we showed that...

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Detalles Bibliográficos
Autores principales: Garcia-Carmona, Yolanda, Ting, Adrian T., Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176016/
https://www.ncbi.nlm.nih.gov/pubmed/30333819
http://dx.doi.org/10.3389/fimmu.2018.02125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176016/
https://www.ncbi.nlm.nih.gov/pubmed/30333819
http://dx.doi.org/10.3389/fimmu.2018.02125

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