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Tracing Antibody Repertoire Evolution by Systems Phylogeny
Antibody evolution studies have been traditionally limited to either tracing a single clonal lineage (B cells derived from a single V-(D)-J recombination) over time or examining bulk functionality changes (e.g., tracing serum polyclonal antibody proteins). Studying a single B cell disregards the maj...
Autores principales: | Yermanos, Alexander Dimitri, Dounas, Andreas Kevin, Stadler, Tanja, Oxenius, Annette, Reddy, Sai T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176079/ https://www.ncbi.nlm.nih.gov/pubmed/30333820 http://dx.doi.org/10.3389/fimmu.2018.02149 |
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