Cargando…

Enzymatic Inactivation of Oxysterols in Breast Tumor Cells Constraints Metastasis Formation by Reprogramming the Metastatic Lung Microenvironment

Recent evidence indicates that immune cells contribute to the formation of tumor metastases by regulating the pre-metastatic niche. Whether tumor-derived factors involved in primary tumor formation play a role in metastasis formation is poorly characterized. Oxysterols act as endogenous regulators o...

Descripción completa

Detalles Bibliográficos
Autores principales: Moresco, Marta A., Raccosta, Laura, Corna, Gianfranca, Maggioni, Daniela, Soncini, Matias, Bicciato, Silvio, Doglioni, Claudio, Russo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176086/
https://www.ncbi.nlm.nih.gov/pubmed/30333826
http://dx.doi.org/10.3389/fimmu.2018.02251