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Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bδ Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in Mice

Alternative splicing enables a gene to give rise to diverse protein products. The Eef1d gene produces two isoforms: a short isoform that encodes translation elongation factor 1Bδ (eEF1Bδ1), and a long isoform that encodes the heat shock-responsive transcription factor eEF1BδL. Previously, we found t...

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Detalles Bibliográficos
Autores principales: Kaitsuka, Taku, Kiyonari, Hiroshi, Shiraishi, Aki, Tomizawa, Kazuhito, Matsushita, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176097/
https://www.ncbi.nlm.nih.gov/pubmed/30333725
http://dx.doi.org/10.3389/fnmol.2018.00358