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Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bδ Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in Mice
Alternative splicing enables a gene to give rise to diverse protein products. The Eef1d gene produces two isoforms: a short isoform that encodes translation elongation factor 1Bδ (eEF1Bδ1), and a long isoform that encodes the heat shock-responsive transcription factor eEF1BδL. Previously, we found t...
Autores principales: | Kaitsuka, Taku, Kiyonari, Hiroshi, Shiraishi, Aki, Tomizawa, Kazuhito, Matsushita, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176097/ https://www.ncbi.nlm.nih.gov/pubmed/30333725 http://dx.doi.org/10.3389/fnmol.2018.00358 |
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