The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis

Chemokines have been shown to be essential players in a range of cancer contexts. In this study, we demonstrate that mice deficient in the atypical chemokine receptor Ackr2 display impaired development of metastasis in vivo in both cell line and spontaneous models. Further analysis reveals that this...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansell, Christopher A. H., Fraser, Alasdair R., Hayes, Alan J., Pingen, Marieke, Burt, Claire L., Lee, Kit Ming, Medina-Ruiz, Laura, Brownlie, Demi, Macleod, Megan K. L., Burgoyne, Paul, Wilson, Gillian J., Nibbs, Robert J. B., Graham, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2018
Materias:
Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176105/
https://www.ncbi.nlm.nih.gov/pubmed/30158126
http://dx.doi.org/10.4049/jimmunol.1800131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176105/
https://www.ncbi.nlm.nih.gov/pubmed/30158126
http://dx.doi.org/10.4049/jimmunol.1800131

Ejemplares similares