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Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population

Genetic factors and gene polymorphisms leading to the onset of autoimmune response in autoimmune hepatitis (AIH) are still not full elucidated. Since the CTLA-4 molecule is a key modulator of the lymphocytes responses we hypothezied that deficiencies or mutations in the gene encoding CTLA4 protein m...

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Detalles Bibliográficos
Autores principales: Chaouali, Marwa, Carvalho, Agostinho, Tezeghdenti, Aymen, Ben Azaiez, Mouna, Cunha, Cristina, Ghazouani, Ezzeddine, Kochkar, Radhia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176120/
https://www.ncbi.nlm.nih.gov/pubmed/30320190
http://dx.doi.org/10.1016/j.gendis.2017.12.006