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Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population
Genetic factors and gene polymorphisms leading to the onset of autoimmune response in autoimmune hepatitis (AIH) are still not full elucidated. Since the CTLA-4 molecule is a key modulator of the lymphocytes responses we hypothezied that deficiencies or mutations in the gene encoding CTLA4 protein m...
Autores principales: | Chaouali, Marwa, Carvalho, Agostinho, Tezeghdenti, Aymen, Ben Azaiez, Mouna, Cunha, Cristina, Ghazouani, Ezzeddine, Kochkar, Radhia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176120/ https://www.ncbi.nlm.nih.gov/pubmed/30320190 http://dx.doi.org/10.1016/j.gendis.2017.12.006 |
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