UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells

UNBS5162, a naphthalimide derivative, has a strong anticancer effect and low clinical hematological toxicity. UNBS5162 has been shown to have an anticancer effect in numerous cancer types, except triple negative breast cancer (TNBC). To explore this issue, TNBC MDA-MB-231 cells were selected, and th...

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Detalles Bibliográficos
Autores principales: Yue, Xin, Li, Mingzhong, Chen, Dongxiang, Xu, Zhenghua, Sun, Shengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176139/
https://www.ncbi.nlm.nih.gov/pubmed/30344670
http://dx.doi.org/10.3892/etm.2018.6675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176139/
https://www.ncbi.nlm.nih.gov/pubmed/30344670
http://dx.doi.org/10.3892/etm.2018.6675

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