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MGCD0103 induces apoptosis and simultaneously increases the expression of NF-κB and PD-L1 in classical Hodgkin's lymphoma

At present there is no consensus on the treatment of classical Hodgkin's lymphoma (CHL) following relapse. The aim of the present study was to access the class I-selective histone deacetylase (HDAC) inhibitor (HDACI) MGCD0103 on the expression levels of Bcl-2, nuclear factor (NF)-κB and program...

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Detalles Bibliográficos
Autores principales: Huang, Renhong, Zhang, Xiaowei, Min, Zhijun, Shadia, Abdelbari Sophia, Yang, Shun'e, Liu, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176203/
https://www.ncbi.nlm.nih.gov/pubmed/30344659
http://dx.doi.org/10.3892/etm.2018.6677