Inhibition of peptidyl-prolyl cis-trans isomerase B mediates cyclosporin A-induced apoptosis of islet β cells

Cyclosporin A (CsA) is widely used as an immunosuppressor in the context of organ transplantation or autoimmune disorders. Recent studies have revealed the detrimental effects of CsA on insulin resistance and pancreatic β cell failure; however, the molecular mechanisms are unknown. The present study...

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Detalles Bibliográficos
Autores principales: Wei, Xiao, Zhu, Dan, Feng, Chenchen, Chen, Guofang, Mao, Xiaodong, Wang, Qifeng, Wang, Jie, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176207/
https://www.ncbi.nlm.nih.gov/pubmed/30344674
http://dx.doi.org/10.3892/etm.2018.6706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176207/
https://www.ncbi.nlm.nih.gov/pubmed/30344674
http://dx.doi.org/10.3892/etm.2018.6706

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