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Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses

The metabolite-sensing G protein–coupled receptors (GPCRs) bind to various metabolites and transmit signals that are important for proper immune and metabolic functions. However, the roles of metabolite-sensing GPCRs in viral infection are not well characterized. Here, we identified metabolite-sensi...

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Detalles Bibliográficos
Autores principales: Xiong, Qingqing, Huang, Hongjun, Wang, Ning, Chen, Ruoyu, Chen, Naiyang, Han, Honghui, Wang, Qin, Siwko, Stefan, Liu, Mingyao, Qian, Min, Du, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176213/
https://www.ncbi.nlm.nih.gov/pubmed/30333836
http://dx.doi.org/10.3389/fimmu.2018.02289