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Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses
The metabolite-sensing G protein–coupled receptors (GPCRs) bind to various metabolites and transmit signals that are important for proper immune and metabolic functions. However, the roles of metabolite-sensing GPCRs in viral infection are not well characterized. Here, we identified metabolite-sensi...
Autores principales: | Xiong, Qingqing, Huang, Hongjun, Wang, Ning, Chen, Ruoyu, Chen, Naiyang, Han, Honghui, Wang, Qin, Siwko, Stefan, Liu, Mingyao, Qian, Min, Du, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176213/ https://www.ncbi.nlm.nih.gov/pubmed/30333836 http://dx.doi.org/10.3389/fimmu.2018.02289 |
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