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CDH13 promoter methylation regulates cisplatin resistance of non-small cell lung cancer cells

Reversing cisplatin resistance of lung cancer cell line A549/DDP through recovering cadherin 13 (CDH13) expression by demethylation was investigated in the current study. RT-PCR was used to measure CDH13 expression in lung cancer A549 and A549/DDP cells with or without 5-Aza-CdR intervention. Methyl...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Zhang, Lei, Yang, Jiasheng, Li, Bin, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176259/
https://www.ncbi.nlm.nih.gov/pubmed/30344726
http://dx.doi.org/10.3892/ol.2018.9325