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DEHP exposure destroys blood-testis barrier (BTB) integrity of immature testes through excessive ROS-mediated autophagy

Di-(2-ethylhexyl) phthalate (DEHP), is known to impair testicular functions and reproduction. However, its effects on immature testis Blood-testis barrier (BTB) and the underlying mechanisms remain obscure. We constructed a rat model to investigate the roles of autophagy in BTB toxicity induced by D...

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Detalles Bibliográficos
Autores principales: Yi, W.E.I., Xiang-Liang, Tang, Yu, Zhou, Bin, Liu, Lian-Ju, Shen, Chun-lan, Long, Tao, L.I.N., Da-wei, H.E., Sheng-de, W.U., Guang-hui, W.E.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176266/
https://www.ncbi.nlm.nih.gov/pubmed/30320191
http://dx.doi.org/10.1016/j.gendis.2018.06.004