DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells

SGI-1027, a novel class of relatively stable, highly lipophilic quinoline-based small-molecule inhibitors of DNA methyltransferase enzymes (DNMTs), is able to inhibit DNMTs activity, and reactivate tumor suppressor genes. However, the potential anticancer mechanisms of SGI-1027 on human hepatocellul...

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Detalles Bibliográficos
Autores principales: Sun, Ning, Zhang, Jialin, Zhang, Chengshuo, Zhao, Bochao, Jiao, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176375/
https://www.ncbi.nlm.nih.gov/pubmed/30344731
http://dx.doi.org/10.3892/ol.2018.9390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176375/
https://www.ncbi.nlm.nih.gov/pubmed/30344731
http://dx.doi.org/10.3892/ol.2018.9390

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