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Epsin15 Homology Domains: Role in the Pathogenesis of Pulmonary Arterial Hypertension

Intersectin-1s (ITSN) deficiency and expression of a biologically active ITSN fragment, result of granzyme B cleavage under inflammatory conditions associated with pulmonary arterial hypertension (PAH), are characteristics of lung tissue of human and animal models of PAH. Recently, we have shown tha...

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Detalles Bibliográficos
Autores principales: Predescu, Dan, Qin, Shanshan, Patel, Monal, Bardita, Cristina, Bhalli, Rabia, Predescu, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176378/
https://www.ncbi.nlm.nih.gov/pubmed/30333761
http://dx.doi.org/10.3389/fphys.2018.01393