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Never-in-mitosis A-related kinase 8, a novel target of von-Hippel-Lindau tumor suppressor protein, promotes gastric cancer cell proliferation

Previous research has revealed that the von-Hippel-Lindau tumor suppressor protein (pVHL) may downregulate never-in-mitosis A-related kinase 8 (NEK8) via hypoxia-inducible factor-α (HIF-α). The HIF-independent functions of pVHL also serve an important role in its tumor-suppressor action. In the pres...

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Detalles Bibliográficos
Autores principales: Ding, Xiao-Fei, Chen, Jie, Zhou, Jun, Chen, Guang, Wu, Ying-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176424/
https://www.ncbi.nlm.nih.gov/pubmed/30333866
http://dx.doi.org/10.3892/ol.2018.9328