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High concordance of TMPRSS-ERG fusion between primary prostate cancer and its lymph node metastases

Approximately 50% of prostate cancer types harbor the transmembrane protease, serine 2: Erythroblast transformation-specific-related gene (ERG) fusion, resulting in oncogenic expression of the ERG transcription factor. ERG represents an attractive target for potential future anticancer therapy in ad...

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Detalles Bibliográficos
Autores principales: Brandi, Franziska, Grupp, Katharina, Hube-Magg, Claudia, Kluth, Martina, Lang, Dagmar, Minner, Sarah, Möller-Koop, Christina, Graefen, Markus, Heinzer, Hans, Tsourlakis, Maria Christina, Wittmer, Corinna, Jacobsen, Frank, Huland, Hartwig, Steurer, Stefan, Lebok, Patrick, Hinsch, Andrea, Wilczak, Waldemar, Schlomm, Thorsten, Simon, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176457/
https://www.ncbi.nlm.nih.gov/pubmed/30333886
http://dx.doi.org/10.3892/ol.2018.9417