Activation of the P2X(7) receptor in midbrain periaqueductal gray participates in the analgesic effect of tramadol in bone cancer pain rats

BACKGROUND: Cancer pain is a well-known serious complication in metastatic or terminal cancer patients. Current pain management remains unsatisfactory. The activation of spinal and supraspinal P2X(7) receptors plays a crucial role in the induction and maintenance mechanisms of various kinds of acute...

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Detalles Bibliográficos
Autores principales: Li, Pengtao, Zhang, Quan, Xiao, Zhi, Yu, Shouyang, Yan, Yan, Qin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176534/
https://www.ncbi.nlm.nih.gov/pubmed/30198382
http://dx.doi.org/10.1177/1744806918803039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176534/
https://www.ncbi.nlm.nih.gov/pubmed/30198382
http://dx.doi.org/10.1177/1744806918803039

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