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Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology

The polymerase-associated factor 1 (Paf1) complex is a general transcription elongation factor of RNA polymerase II, which is composed of five core subunits, Paf1, Ctr9, Cdc73, Leo1, and Rtf1, and functions as a diverse platform that broadly affects gene expression genome-wide. In this study, we sol...

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Detalles Bibliográficos
Autores principales: Deng, Pujuan, Zhou, Yuqiao, Jiang, Junyi, Li, Haojie, Tian, Wei, Cao, Yinghua, Qin, Yan, Kim, Jaehoon, Roeder, Robert G., Patel, Dinshaw J., Wang, Zhanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176576/
https://www.ncbi.nlm.nih.gov/pubmed/30224485
http://dx.doi.org/10.1073/pnas.1812256115