IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes

Proinflammatory cytokine signaling in keratinocytes plays a crucial role in the pathogenesis of psoriasis, a skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes and infiltration of inflammatory cells. Although IL-17A and TNFα are effective therapeutic targe...

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Detalles Bibliográficos
Autores principales: Müller, Anne, Hennig, André, Lorscheid, Sebastian, Grondona, Paula, Schulze-Osthoff, Klaus, Hailfinger, Stephan, Kramer, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176600/
https://www.ncbi.nlm.nih.gov/pubmed/30224457
http://dx.doi.org/10.1073/pnas.1801377115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176600/
https://www.ncbi.nlm.nih.gov/pubmed/30224457
http://dx.doi.org/10.1073/pnas.1801377115

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