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IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes

Proinflammatory cytokine signaling in keratinocytes plays a crucial role in the pathogenesis of psoriasis, a skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes and infiltration of inflammatory cells. Although IL-17A and TNFα are effective therapeutic targe...

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Detalles Bibliográficos
Autores principales:	Müller, Anne, Hennig, André, Lorscheid, Sebastian, Grondona, Paula, Schulze-Osthoff, Klaus, Hailfinger, Stephan, Kramer, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176600/ https://www.ncbi.nlm.nih.gov/pubmed/30224457 http://dx.doi.org/10.1073/pnas.1801377115

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