Successful sequential treatment of refractory tumors caused by small cell carcinoma transformation and EGFR-T790M mutation diagnosed by repeated genetic testing in a patient with lung adenocarcinoma harboring epidermal growth factor receptor mutations: A case report

NSCLC patients with EGFR mutations respond to EGFR-TKIs; however, the management of refractory tumors to EGFR-TKIs remains unclear. We demonstrated that repeated genetic testing might be useful for detecting resistance mechanisms as well as for decision-making in EGFR mutated NSCLC patients, followi...

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Detalles Bibliográficos
Autores principales: Nishioka, Naoya, Yamada, Tadaaki, Harita, Sachi, Hirai, Soichi, Katayama, Yuki, Nakano, Takayuki, Okura, Naoko, Tamiya, Nobuyo, Kaneko, Yoshiko, Uchino, Junji, Takayama, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176787/
https://www.ncbi.nlm.nih.gov/pubmed/30310765
http://dx.doi.org/10.1016/j.rmcr.2018.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176787/
https://www.ncbi.nlm.nih.gov/pubmed/30310765
http://dx.doi.org/10.1016/j.rmcr.2018.10.004

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