Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe(2)O(3) nanoparticles towards human tumor cells

Doxorubicin-conjugated magnetic nanoparticles containing hydrolyzable hydrazone bonds were developed using a non-toxic poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) coating, which ensured good colloidal stability in aqueous media and limited internalization by the cells, however, enabled adhesion...

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Detalles Bibliográficos
Autores principales: Plichta, Zdeněk, Kozak, Yulia, Panchuk, Rostyslav, Sokolova, Viktoria, Epple, Matthias, Kobylinska, Lesya, Jendelová, Pavla, Horák, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176839/
https://www.ncbi.nlm.nih.gov/pubmed/30345216
http://dx.doi.org/10.3762/bjnano.9.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176839/
https://www.ncbi.nlm.nih.gov/pubmed/30345216
http://dx.doi.org/10.3762/bjnano.9.236

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