Cargando…

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe(2)O(3) nanoparticles towards human tumor cells

Doxorubicin-conjugated magnetic nanoparticles containing hydrolyzable hydrazone bonds were developed using a non-toxic poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) coating, which ensured good colloidal stability in aqueous media and limited internalization by the cells, however, enabled adhesion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Plichta, Zdeněk, Kozak, Yulia, Panchuk, Rostyslav, Sokolova, Viktoria, Epple, Matthias, Kobylinska, Lesya, Jendelová, Pavla, Horák, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2018
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176839/ https://www.ncbi.nlm.nih.gov/pubmed/30345216 http://dx.doi.org/10.3762/bjnano.9.236

Ejemplares similares

Synthesis, Morphology, and Rheological Evaluation of HPMA (N-2-Hydroxypropyl Methacrylamide)-PCL (Polycaprolactone) Conjugates
por: Rani, Sarita, et al.
Publicado: (2021)

N-(2-hydroxypropyl)methacrylamide–amphotericin B (HPMA–AmB) copolymer conjugates as antileishmanial agents
por: Nicoletti, Salvatore, et al.
Publicado: (2009)

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro.
por: Duncan, R., et al.
Publicado: (1987)

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia.
por: Duncan, R., et al.
Publicado: (1988)

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.
por: Seymour, L. W., et al.
Publicado: (1991)

Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins
por: Janisova, Larisa, et al.
Publicado: (2020)

Internal Structure of Thermoresponsive Physically Crosslinked Nanogel of Poly[N-(2-hydroxypropyl)methacrylamide]-Block-Poly[N-(2,2-difluoroethyl)acrylamide], Prominent (19)F MRI Tracer
por: Babuka, David, et al.
Publicado: (2020)

Reproductive toxicology. Methacrylamide.
Publicado: (1997)

Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat.
por: Wedge, S. R., et al.
Publicado: (1991)

The use of poly(N-[2-hydroxypropyl]-methacrylamide) hydrogel to repair a T10 spinal cord hemisection in rat: a behavioural, electrophysiological and anatomical examination
por: Pertici, Vincent, et al.
Publicado: (2013)

Tissue-protective activity of selenomethionine and D-panthetine in B16 melanoma-bearing mice under doxorubicin treatment is not connected with their ROS scavenging potential
por: Panchuk, Rostyslav R., et al.
Publicado: (2017)

Antioxidants selenomethionine and D-pantethine decrease the negative side effects of doxorubicin in NL/Ly lymphoma-bearing mice
por: Panchuk, Rostyslav R., et al.
Publicado: (2016)

Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry
por: Reddi, Rambabu N., et al.
Publicado: (2021)

Synthesis, characterization and osteogenesis of phosphorylated methacrylamide chitosan hydrogels
por: Yang, Huishang, et al.
Publicado: (2018)

Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly[N-(2-Hydroxypropyl)Methacrylamide] as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model
por: Novy, Zbynek, et al.
Publicado: (2020)

Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study
por: Panchuk, Rostyslav, et al.
Publicado: (2014)

Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells
por: Коbylinska, Lesya I., et al.
Publicado: (2017)

Complex of C(60) Fullerene with Doxorubicin as a Promising Agent in Antitumor Therapy
por: Prylutska, Svitlana V., et al.
Publicado: (2015)

Electrical Response of Poly(N-[3-(dimethylamino)Propyl] Methacrylamide) to CO(2) at a Long Exposure Period
por: Shahrbabaki, Zahra, et al.
Publicado: (2022)

Reversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier
por: Li, Jin-Ming, et al.
Publicado: (2015)

Fluorinated methacrylamide chitosan hydrogel dressings enhance healing in an acute porcine wound model
por: Patil, Pritam S., et al.
Publicado: (2018)

Therapeutic Strategies for Spinal Cord Injury
por: Jendelova, Pavla
Publicado: (2018)

Covalent Conjugate of Ser-Pro-Cys Tripeptide with PEGylated Comb-Like Polymer as Novel Killer of Human Tumor Cells
por: Manko, Nazar, et al.
Publicado: (2022)

Losartan Interactions with 2-Hydroxypropyl-β-CD
por: Palli, Vasiliki, et al.
Publicado: (2022)

Doxorubicin·Hydrochloride/Cisplatin-Loaded Hydrogel/Nanosized (2-Hydroxypropyl)-Beta-Cyclodextrin Local Drug-Delivery System for Osteosarcoma Treatment In Vivo
por: Yoon, Sun Jung, et al.
Publicado: (2019)

Ultrasensitive (Co)polymers Based on Poly(methacrylamide) Structure with Fining-Tunable pH Responsive Value
por: Fan, Haiming, et al.
Publicado: (2018)

Acetylenic Replacement of Albicidin's Methacrylamide Residue Circumvents Detrimental E/Z Photoisomerization and Preserves Antibacterial Activity
por: Behroz, Iraj, et al.
Publicado: (2021)

In vitro study of the anticancer activity of various doxorubicin-containing dispersions
por: Matvienko, Tatiana, et al.
Publicado: (2019)

The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
por: Butowska, Kamila, et al.
Publicado: (2020)

Combinations of Piperine with Hydroxypropyl-β-Cyclodextrin as a Multifunctional System
por: Stasiłowicz, Anna, et al.
Publicado: (2021)

Gelatin-methacrylamide gel loaded with microspheres to deliver GDNF in bilayer collagen conduit promoting sciatic nerve growth
por: Zhuang, Hai, et al.
Publicado: (2016)

Effect of Hydrophobic Interactions on Lower Critical Solution Temperature for Poly(N-isopropylacrylamide-co-dopamine Methacrylamide) Copolymers
por: García-Peñas, Alberto, et al.
Publicado: (2019)

RGDS-Modified Superporous Poly(2-Hydroxyethyl Methacrylate)-Based Scaffolds as 3D In Vitro Leukemia Model
por: Svozilová, Hana, et al.
Publicado: (2021)

The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells
por: Babic, Michal, et al.
Publicado: (2012)

Magnetic Temperature-Sensitive Solid-Lipid Particles for Targeting and Killing Tumor Cells
por: Świętek, Małgorzata, et al.
Publicado: (2020)

In Situ Immobilization on the Silica Gel Surface and Adsorption Capacity of Poly[N-(4-carboxyphenyl)methacrylamide] on Toxic Metal Ions
por: Yanovska, Elina, et al.
Publicado: (2017)

Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
por: Moral-Zamorano, María, et al.
Publicado: (2021)

Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
por: Soto, Altea, et al.
Publicado: (2023)

Cannabimimetic N-Stearoylethanolamine as “Double-Edged Sword” in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo
por: Panchuk, Rostyslav, et al.
Publicado: (2023)

Formation of inclusion complex of enrofloxacin with 2-hydroxypropyl-β-cyclodextrin
por: Ding, Yili, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uqbch5jlj65cgfgs6i0vi1ra67