Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

BACKGROUND: Coronary artery disease (CAD) has substantial heritability and a polygenic architecture. However, the potential of genomic risk scores to help predict CAD outcomes has not been evaluated comprehensively, because available studies have involved limited genomic scope and limited sample siz...

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Detalles Bibliográficos
Autores principales: Inouye, Michael, Abraham, Gad, Nelson, Christopher P., Wood, Angela M., Sweeting, Michael J., Dudbridge, Frank, Lai, Florence Y., Kaptoge, Stephen, Brozynska, Marta, Wang, Tingting, Ye, Shu, Webb, Thomas R., Rutter, Martin K., Tzoulaki, Ioanna, Patel, Riyaz S., Loos, Ruth J.F., Keavney, Bernard, Hemingway, Harry, Thompson, John, Watkins, Hugh, Deloukas, Panos, Di Angelantonio, Emanuele, Butterworth, Adam S., Danesh, John, Samani, Nilesh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176870/
https://www.ncbi.nlm.nih.gov/pubmed/30309464
http://dx.doi.org/10.1016/j.jacc.2018.07.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176870/
https://www.ncbi.nlm.nih.gov/pubmed/30309464
http://dx.doi.org/10.1016/j.jacc.2018.07.079

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