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Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

Intestinal mesenchymal cells play essential roles in epithelial homeostasis, matrix remodeling, immunity, and inflammation. But the extent of heterogeneity within the colonic mesenchyme in these processes remains unknown. Using unbiased single-cell profiling of over 16,500 colonic mesenchymal cells,...

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Detalles Bibliográficos
Autores principales: Kinchen, James, Chen, Hannah H., Parikh, Kaushal, Antanaviciute, Agne, Jagielowicz, Marta, Fawkner-Corbett, David, Ashley, Neil, Cubitt, Laura, Mellado-Gomez, Esther, Attar, Moustafa, Sharma, Eshita, Wills, Quin, Bowden, Rory, Richter, Felix C., Ahern, David, Puri, Kamal D., Henault, Jill, Gervais, Francois, Koohy, Hashem, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176871/
https://www.ncbi.nlm.nih.gov/pubmed/30270042
http://dx.doi.org/10.1016/j.cell.2018.08.067